BDBM50295978 (3R,6R,7aS)-6-amino-5-oxo-6-phenethylhexahydropyrrolo[2,1-b]thiazole-3-carbonitrile hydrochloride::CHEMBL558313

SMILES: N[C@]1(CCc2ccccc2)C[C@@H]2SC[C@@H](C#N)N2C1=O

InChI Key: InChIKey=VBKFPTDUXZKHJG-VNHYZAJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50295978 ((3R,6R,7aS)-6-amino-5-oxo-6-phenethylhexahydropyrr...) Show SMILES N[C@]1(CCc2ccccc2)C[C@@H]2SC[C@@H](C#N)N2C1=O |r| Show InChI InChI=1S/C15H17N3OS/c16-9-12-10-20-13-8-15(17,14(19)18(12)13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-8,10,17H2/t12-,13+,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Phenomix Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 by fluorescence assay				Bioorg Med Chem Lett 19: 4437-40 (2009) Article DOI: 10.1016/j.bmcl.2009.05.048 BindingDB Entry DOI: 10.7270/Q2571C1Z
					More data for this Ligand-Target Pair
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50295978 ((3R,6R,7aS)-6-amino-5-oxo-6-phenethylhexahydropyrr...) Show SMILES N[C@]1(CCc2ccccc2)C[C@@H]2SC[C@@H](C#N)N2C1=O |r| Show InChI InChI=1S/C15H17N3OS/c16-9-12-10-20-13-8-15(17,14(19)18(12)13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-8,10,17H2/t12-,13+,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Phenomix Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant FAP expressed in Sf9 cells by fluorescence assay				Bioorg Med Chem Lett 19: 4437-40 (2009) Article DOI: 10.1016/j.bmcl.2009.05.048 BindingDB Entry DOI: 10.7270/Q2571C1Z
					More data for this Ligand-Target Pair