BindingDB logo
myBDB logout

null

SMILES: CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccco1

InChI Key: InChIKey=YPGAYOUQBDJBPU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296056   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock factor protein 1


(Homo sapiens (Human))		BDBM50296056
PNG
(1-ethyl-3-(furan-2-yl)-6-methylpyrimido[5,4-e][1,2...)
Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccco1
Show InChI InChI=1S/C12H11N5O3/c1-3-17-10-8(11(18)16(2)12(19)14-10)13-9(15-17)7-5-4-6-20-7/h4-6H,3H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 1.01E+4n/an/an/an/a



CytRx Corporation

Curated by ChEMBL


Assay Description
Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...

Bioorg Med Chem Lett 19: 4303-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.073
BindingDB Entry DOI: 10.7270/Q2HD7VPC
More data for this
Ligand-Target Pair