BDBM50296063 3-(1H-benzo[d]imidazol-2-yl)-1-butyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione::CHEMBL557716

SMILES: CCCCn1nc(nc2c1nc(=O)n(C)c2=O)-c1nc2ccccc2[nH]1

InChI Key: InChIKey=IOKNAOGAUUFHHA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock factor protein 1 (Homo sapiens (Human))	BDBM50296063 (3-(1H-benzo[d]imidazol-2-yl)-1-butyl-6-methylpyrim...) Show SMILES CCCCn1nc(nc2c1nc(=O)n(C)c2=O)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C17H17N7O2/c1-3-4-9-24-15-12(16(25)23(2)17(26)21-15)20-14(22-24)13-18-10-7-5-6-8-11(10)19-13/h5-8H,3-4,9H2,1-2H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.08E+4	n/a	n/a	n/a	n/a
CytRx Corporation Curated by ChEMBL					Assay Description Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...				Bioorg Med Chem Lett 19: 4303-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.073 BindingDB Entry DOI: 10.7270/Q2HD7VPC
					More data for this Ligand-Target Pair