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SMILES: CCCCn1nc(nc2c1nc(=O)n(C)c2=O)-c1nc2ccccc2s1

InChI Key: InChIKey=REUQOCZUYLFNNL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296065   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock factor protein 1


(Homo sapiens (Human))		BDBM50296065
PNG
(3-(benzo[d]thiazol-2-yl)-1-butyl-6-methylpyrimido[...)
Show SMILES CCCCn1nc(nc2c1nc(=O)n(C)c2=O)-c1nc2ccccc2s1
Show InChI InChI=1S/C17H16N6O2S/c1-3-4-9-23-14-12(16(24)22(2)17(25)20-14)19-13(21-23)15-18-10-7-5-6-8-11(10)26-15/h5-8H,3-4,9H2,1-2H3
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Article
PubMed
n/an/an/an/a 2.50E+3n/an/an/an/a



CytRx Corporation

Curated by ChEMBL


Assay Description
Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...

Bioorg Med Chem Lett 19: 4303-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.073
BindingDB Entry DOI: 10.7270/Q2HD7VPC
More data for this
Ligand-Target Pair