BDBM50296072 1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide::CHEMBL558247

SMILES: CCn1nc(-c2ccc(C)s2)[n+]([O-])c2c1nc(=O)n(C)c2=O

InChI Key: InChIKey=TZQKVBGHIPGWQO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock factor protein 1 (Homo sapiens (Human))	BDBM50296072 (1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dio...) Show SMILES CCn1nc(-c2ccc(C)s2)[n+]([O-])c2c1nc(=O)n(C)c2=O Show InChI InChI=1S/C13H13N5O3S/c1-4-17-11-9(12(19)16(3)13(20)14-11)18(21)10(15-17)8-6-5-7(2)22-8/h5-6H,4H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a
CytRx Corporation Curated by ChEMBL					Assay Description Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...				Bioorg Med Chem Lett 19: 4303-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.073 BindingDB Entry DOI: 10.7270/Q2HD7VPC
					More data for this Ligand-Target Pair