BDBM50296583 (1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3-yl)-4-methyl-1H-pyrazol-3-yl)methyl)cyclopentanamine::CHEMBL557653

SMILES: Cc1c(CN[C@H]2CC[C@@H](F)C2)[nH]nc1-c1cnc(C)c(F)c1

InChI Key: InChIKey=HGMBWWNKONNNTI-OLZOCXBDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50296583 ((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...) Show SMILES Cc1c(CN[C@H]2CC[C@@H](F)C2)[nH]nc1-c1cnc(C)c(F)c1 |r| Show InChI InChI=1S/C16H20F2N4/c1-9-15(8-20-13-4-3-12(17)6-13)21-22-16(9)11-5-14(18)10(2)19-7-11/h5,7,12-13,20H,3-4,6,8H2,1-2H3,(H,21,22)/t12-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptor				Bioorg Med Chem Lett 19: 4729-32 (2009) Article DOI: 10.1016/j.bmcl.2009.06.051 BindingDB Entry DOI: 10.7270/Q2H9958F
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50296583 ((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...) Show SMILES Cc1c(CN[C@H]2CC[C@@H](F)C2)[nH]nc1-c1cnc(C)c(F)c1 |r| Show InChI InChI=1S/C16H20F2N4/c1-9-15(8-20-13-4-3-12(17)6-13)21-22-16(9)11-5-14(18)10(2)19-7-11/h5,7,12-13,20H,3-4,6,8H2,1-2H3,(H,21,22)/t12-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at ORL1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4729-32 (2009) Article DOI: 10.1016/j.bmcl.2009.06.051 BindingDB Entry DOI: 10.7270/Q2H9958F
					More data for this Ligand-Target Pair