BDBM50296766 CHEMBL557723::N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)cyclopentanecarboxamide
SMILES: N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CCCC1)Cc1cc(F)c(F)cc1F
InChI Key: InChIKey=BNJKISKKEISOIC-CVEARBPZSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50296766![]() (CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human human liver microsomes by mass spectrometry | Bioorg Med Chem Lett 19: 4818-23 (2009) Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50296766![]() (CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of DPP7 | Bioorg Med Chem Lett 19: 4818-23 (2009) Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50296766![]() (CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of DPP4 | Bioorg Med Chem Lett 19: 4818-23 (2009) Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase VIII (Homo sapiens (Human)) | BDBM50296766![]() (CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human recombinant DPP8 | Bioorg Med Chem Lett 19: 4818-23 (2009) Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM50296766![]() (CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human recombinant DPP9 | Bioorg Med Chem Lett 19: 4818-23 (2009) Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 | |||||||||||
More data for this Ligand-Target Pair |