BDBM50296961 (R)-4'-(2-(2-(3-aminophenyl)-2-hydroxyethylamino)ethyl)-3-isopropoxy-N-(methylsulfonyl)biphenyl-4-carboxamide::CHEMBL562395

SMILES: CC(C)Oc1cc(ccc1C(=O)NS(C)(=O)=O)-c1ccc(CCNC[C@H](O)c2cccc(N)c2)cc1

InChI Key: InChIKey=GKJRPWPPZIETKU-VWLOTQADSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50296961 ((R)-4'-(2-(2-(3-aminophenyl)-2-hydroxyethylamino)e...) Show SMILES CC(C)Oc1cc(ccc1C(=O)NS(C)(=O)=O)-c1ccc(CCNC[C@H](O)c2cccc(N)c2)cc1 |r| Show InChI InChI=1S/C27H33N3O5S/c1-18(2)35-26-16-21(11-12-24(26)27(32)30-36(3,33)34)20-9-7-19(8-10-20)13-14-29-17-25(31)22-5-4-6-23(28)15-22/h4-12,15-16,18,25,29,31H,13-14,17,28H2,1-3H3,(H,30,32)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme im...				Bioorg Med Chem Lett 19: 4679-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.083 BindingDB Entry DOI: 10.7270/Q2S183DR
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50296961 ((R)-4'-(2-(2-(3-aminophenyl)-2-hydroxyethylamino)e...) Show SMILES CC(C)Oc1cc(ccc1C(=O)NS(C)(=O)=O)-c1ccc(CCNC[C@H](O)c2cccc(N)c2)cc1 |r| Show InChI InChI=1S/C27H33N3O5S/c1-18(2)35-26-16-21(11-12-24(26)27(32)30-36(3,33)34)20-9-7-19(8-10-20)13-14-29-17-25(31)22-5-4-6-23(28)15-22/h4-12,15-16,18,25,29,31H,13-14,17,28H2,1-3H3,(H,30,32)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme imm...				Bioorg Med Chem Lett 19: 4679-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.083 BindingDB Entry DOI: 10.7270/Q2S183DR
					More data for this Ligand-Target Pair