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SMILES: [#6]-[#8]-c1ccc(-[#8])c(c1)-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]-c2ccc3cc(F)ccc3c2)-[#6]-1

InChI Key: InChIKey=ZNFBEAQCHXSVEN-RUZDIDTESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297176   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50297176
PNG
(CHEMBL562574 | N-{(3R)-1-[(6-Fluoro-2-naphthyl)met...)
Show SMILES [#6]-[#8]-c1ccc(-[#8])c(c1)-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]-c2ccc3cc(F)ccc3c2)-[#6]-1 |r|
Show InChI InChI=1S/C30H32FN3O4/c1-38-26-6-7-28(35)27(17-26)30(37)34-12-8-20(9-13-34)15-29(36)32-25-10-11-33(19-25)18-21-2-3-23-16-24(31)5-4-22(23)14-21/h2-7,14-17,25,35H,8-13,18-19H2,1H3,(H,32,36)/t25-/m1/s1
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Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux

Bioorg Med Chem 17: 5989-6002 (2009)


Article DOI: 10.1016/j.bmc.2009.06.066
BindingDB Entry DOI: 10.7270/Q2WD40NV
More data for this
Ligand-Target Pair