BDBM50297193 CHEMBL551205::N-({1-[(6-Fluoro-2-naphthyl)methyl]piperidin-4-yl}carbamoyl)benzenesulfonamide

SMILES: Fc1ccc2cc(CN3CCC(CC3)NC(=O)NS(=O)(=O)c3ccccc3)ccc2c1

InChI Key: InChIKey=SFPGIRFFPMPQLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50297193 (CHEMBL551205 | N-({1-[(6-Fluoro-2-naphthyl)methyl]...) Show SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)NS(=O)(=O)c3ccccc3)ccc2c1 Show InChI InChI=1S/C23H24FN3O3S/c24-20-9-8-18-14-17(6-7-19(18)15-20)16-27-12-10-21(11-13-27)25-23(28)26-31(29,30)22-4-2-1-3-5-22/h1-9,14-15,21H,10-13,16H2,(H2,25,26,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux				Bioorg Med Chem 17: 5989-6002 (2009) Article DOI: 10.1016/j.bmc.2009.06.066 BindingDB Entry DOI: 10.7270/Q2WD40NV
					More data for this Ligand-Target Pair