BDBM50297196 CHEMBL557936::N-{1-[(6-Fluoro-2-naphthyl)methyl]piperidin-4-yl}-2-phenylacetamide

SMILES: Fc1ccc2cc(CN3CCC(CC3)NC(=O)Cc3ccccc3)ccc2c1

InChI Key: InChIKey=UXWIDVSISZLIAE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50297196 (CHEMBL557936 | N-{1-[(6-Fluoro-2-naphthyl)methyl]p...) Show SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)Cc3ccccc3)ccc2c1 Show InChI InChI=1S/C24H25FN2O/c25-22-9-8-20-14-19(6-7-21(20)16-22)17-27-12-10-23(11-13-27)26-24(28)15-18-4-2-1-3-5-18/h1-9,14,16,23H,10-13,15,17H2,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux				Bioorg Med Chem 17: 5989-6002 (2009) Article DOI: 10.1016/j.bmc.2009.06.066 BindingDB Entry DOI: 10.7270/Q2WD40NV
					More data for this Ligand-Target Pair