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SMILES: Fc1ccc2cc(CN3CCC(C3)C(=O)c3ccccc3-c3ccccc3)ccc2c1

InChI Key: InChIKey=GVJBLPDTPTULKQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297201   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50297201
PNG
(CHEMBL561941 | N-{(rac)-1-[(6-Fluoro-2-naphthyl)me...)
Show SMILES Fc1ccc2cc(CN3CCC(C3)C(=O)c3ccccc3-c3ccccc3)ccc2c1
Show InChI InChI=1S/C28H24FNO/c29-25-13-12-22-16-20(10-11-23(22)17-25)18-30-15-14-24(19-30)28(31)27-9-5-4-8-26(27)21-6-2-1-3-7-21/h1-13,16-17,24H,14-15,18-19H2
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n/an/a 320n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux

Bioorg Med Chem 17: 5989-6002 (2009)


Article DOI: 10.1016/j.bmc.2009.06.066
BindingDB Entry DOI: 10.7270/Q2WD40NV
More data for this
Ligand-Target Pair