Found 6 hits for monomerid = 50297233 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP1 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-14 (MMP14)
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP14 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
(Homo sapiens (Human)) | BDBM50297233
![PNG](/data/jpeg/tenK5029/BindingDB_50297233.png) ((S)-3-methyl-2-(4'-(3-methyl-4-(methylsulfonamido)...)Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2oc3cccc(NS(C)(=O)=O)c3c2C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H29N3O8S2/c1-16(2)25(28(33)34)31-41(37,38)21-14-10-19(11-15-21)18-8-12-20(13-9-18)29-27(32)26-17(3)24-22(30-40(4,35)36)6-5-7-23(24)39-26/h5-16,25,30-31H,1-4H3,(H,29,32)(H,33,34)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of aggrecanase-1 |
Bioorg Med Chem Lett 19: 4546-50 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.008 BindingDB Entry DOI: 10.7270/Q2MW2H6T |
More data for this Ligand-Target Pair | |