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SMILES: CN(C)CCc1sc2ccccc2c1Cc1cnccn1

InChI Key: InChIKey=QWTQKWHOWDAFRM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297311   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50297311
PNG
(CHEMBL551340 | Dimethyl-[2-(3-pyrazin-2-ylmethyl-b...)
Show SMILES CN(C)CCc1sc2ccccc2c1Cc1cnccn1
Show InChI InChI=1S/C17H19N3S/c1-20(2)10-7-17-15(11-13-12-18-8-9-19-13)14-5-3-4-6-16(14)21-17/h3-6,8-9,12H,7,10-11H2,1-2H3
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 75n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting

J Med Chem 52: 5307-10 (2009)


Article DOI: 10.1021/jm900933k
BindingDB Entry DOI: 10.7270/Q2057G0S
More data for this
Ligand-Target Pair