null

SMILES: Cc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1

InChI Key: InChIKey=ARHPVLJEWVJHQV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298005 (2-fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-...) Show SMILES Cc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1 |c:9| Show InChI InChI=1S/C12H10FN3O3/c1-6-14-12(16-18-6)11-5-9(15-19-11)7-2-3-10(17)8(13)4-7/h2-4,11,17H,5H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298005 (2-fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-...) Show SMILES Cc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1 |c:9| Show InChI InChI=1S/C12H10FN3O3/c1-6-14-12(16-18-6)11-5-9(15-19-11)7-2-3-10(17)8(13)4-7/h2-4,11,17H,5H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair