null

SMILES: COc1ccc(cc1F)C1=NOC(C1)c1noc(CCC(=O)NC2CCCCC2)n1

InChI Key: InChIKey=ZZAGRYXNNMXCKX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298009 (CHEMBL559125 | N-cyclohexyl-3(3-(3-(3-fluoro-4-met...) Show SMILES COc1ccc(cc1F)C1=NOC(C1)c1noc(CCC(=O)NC2CCCCC2)n1 |t:10| Show InChI InChI=1S/C21H25FN4O4/c1-28-17-8-7-13(11-15(17)22)16-12-18(29-25-16)21-24-20(30-26-21)10-9-19(27)23-14-5-3-2-4-6-14/h7-8,11,14,18H,2-6,9-10,12H2,1H3,(H,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298009 (CHEMBL559125 | N-cyclohexyl-3(3-(3-(3-fluoro-4-met...) Show SMILES COc1ccc(cc1F)C1=NOC(C1)c1noc(CCC(=O)NC2CCCCC2)n1 |t:10| Show InChI InChI=1S/C21H25FN4O4/c1-28-17-8-7-13(11-15(17)22)16-12-18(29-25-16)21-24-20(30-26-21)10-9-19(27)23-14-5-3-2-4-6-14/h7-8,11,14,18H,2-6,9-10,12H2,1H3,(H,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair