null

SMILES: COC(=O)CCc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1

InChI Key: InChIKey=QVOODYQAHMMUQF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298011 (CHEMBL563301 | methyl 3-(3-(3(3-fluoro-4hydroxyphe...) Show SMILES COC(=O)CCc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1 |c:14| Show InChI InChI=1S/C15H14FN3O5/c1-22-14(21)5-4-13-17-15(19-24-13)12-7-10(18-23-12)8-2-3-11(20)9(16)6-8/h2-3,6,12,20H,4-5,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298011 (CHEMBL563301 | methyl 3-(3-(3(3-fluoro-4hydroxyphe...) Show SMILES COC(=O)CCc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1 |c:14| Show InChI InChI=1S/C15H14FN3O5/c1-22-14(21)5-4-13-17-15(19-24-13)12-7-10(18-23-12)8-2-3-11(20)9(16)6-8/h2-3,6,12,20H,4-5,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair