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SMILES: Oc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(O)c1O

InChI Key: InChIKey=HGAIFEYVWWLSNQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298014 (3-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...) Show SMILES Oc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(O)c1O |t:9| Show InChI InChI=1S/C17H12FN3O5/c18-10-6-8(4-5-12(10)22)11-7-14(25-20-11)16-19-17(26-21-16)9-2-1-3-13(23)15(9)24/h1-6,14,22-24H,7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298014 (3-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...) Show SMILES Oc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(O)c1O |t:9| Show InChI InChI=1S/C17H12FN3O5/c18-10-6-8(4-5-12(10)22)11-7-14(25-20-11)16-19-17(26-21-16)9-2-1-3-13(23)15(9)24/h1-6,14,22-24H,7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair