null

SMILES: Oc1ccc(cc1F)C1=NOC(CCNC(=O)c2ccc(F)cc2)C1

InChI Key: InChIKey=UAPQSURMMCXUFR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298021 (4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...) Show SMILES Oc1ccc(cc1F)C1=NOC(CCNC(=O)c2ccc(F)cc2)C1 |t:9| Show InChI InChI=1S/C18H16F2N2O3/c19-13-4-1-11(2-5-13)18(24)21-8-7-14-10-16(22-25-14)12-3-6-17(23)15(20)9-12/h1-6,9,14,23H,7-8,10H2,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298021 (4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...) Show SMILES Oc1ccc(cc1F)C1=NOC(CCNC(=O)c2ccc(F)cc2)C1 |t:9| Show InChI InChI=1S/C18H16F2N2O3/c19-13-4-1-11(2-5-13)18(24)21-8-7-14-10-16(22-25-14)12-3-6-17(23)15(20)9-12/h1-6,9,14,23H,7-8,10H2,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISA				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298021 (4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...) Show SMILES Oc1ccc(cc1F)C1=NOC(CCNC(=O)c2ccc(F)cc2)C1 |t:9| Show InChI InChI=1S/C18H16F2N2O3/c19-13-4-1-11(2-5-13)18(24)21-8-7-14-10-16(22-25-14)12-3-6-17(23)15(20)9-12/h1-6,9,14,23H,7-8,10H2,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair