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SMILES: CCCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=WBAATNCDCBYLGO-HNNXBMFYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298039   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50298039
PNG
((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...)
Show SMILES CCCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r|
Show InChI InChI=1S/C16H22ClN3/c1-3-4-8-20(15-7-9-19(2)12-15)14-6-5-13(11-18)16(17)10-14/h5-6,10,15H,3-4,7-9,12H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay


Bioorg Med Chem Lett 19: 4777-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.055
BindingDB Entry DOI: 10.7270/Q2TB16XG
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50298039
PNG
((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...)
Show SMILES CCCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r|
Show InChI InChI=1S/C16H22ClN3/c1-3-4-8-20(15-7-9-19(2)12-15)14-6-5-13(11-18)16(17)10-14/h5-6,10,15H,3-4,7-9,12H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to PR by fluorescence polarization based competition binding assay


Bioorg Med Chem Lett 19: 4777-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.055
BindingDB Entry DOI: 10.7270/Q2TB16XG
More data for this
Ligand-Target Pair