BDBM50298265 CHEMBL582839::N-(1-(Hydroxyamino)-5-(3-nitroguanidino)-1-oxopentan-2-yl)-2-naphthamide

SMILES: NC(NCCC[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)=N[N+]([O-])=O

InChI Key: InChIKey=DHENBWAOBADTQO-AWEZNQCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50298265 (CHEMBL582839 | N-(1-(Hydroxyamino)-5-(3-nitroguani...) Show SMILES NC(NCCC[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)=N[N+]([O-])=O |r,w:24.26| Show InChI InChI=1S/C17H20N6O5/c18-17(21-23(27)28)19-9-3-6-14(16(25)22-26)20-15(24)13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,14,26H,3,6,9H2,(H,20,24)(H,22,25)(H3,18,19,21)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem 17: 4666-73 (2009) Article DOI: 10.1016/j.bmc.2009.04.056 BindingDB Entry DOI: 10.7270/Q2D21XN3
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50298265 (CHEMBL582839 | N-(1-(Hydroxyamino)-5-(3-nitroguani...) Show SMILES NC(NCCC[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)=N[N+]([O-])=O |r,w:24.26| Show InChI InChI=1S/C17H20N6O5/c18-17(21-23(27)28)19-9-3-6-14(16(25)22-26)20-15(24)13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,14,26H,3,6,9H2,(H,20,24)(H,22,25)(H3,18,19,21)/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry				Bioorg Med Chem 17: 4666-73 (2009) Article DOI: 10.1016/j.bmc.2009.04.056 BindingDB Entry DOI: 10.7270/Q2D21XN3
					More data for this Ligand-Target Pair