BDBM50299361 CHEMBL575962::N2-cyclopentyl-6-(piperazin-1-yl)-N4-(pyridin-4-yl)-1,3,5-triazine-2,4-diamine

SMILES: C1CCC(C1)Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1

InChI Key: InChIKey=QQVDBGDYWFLERO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50299361 (CHEMBL575962 | N2-cyclopentyl-6-(piperazin-1-yl)-N...) Show SMILES C1CCC(C1)Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1 Show InChI InChI=1S/C17H24N8/c1-2-4-13(3-1)20-15-22-16(21-14-5-7-18-8-6-14)24-17(23-15)25-11-9-19-10-12-25/h5-8,13,19H,1-4,9-12H2,(H2,18,20,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of ROCK1 by IMAP assay				Bioorg Med Chem Lett 19: 6027-31 (2009) Article DOI: 10.1016/j.bmcl.2009.09.046 BindingDB Entry DOI: 10.7270/Q2668D7P
					More data for this Ligand-Target Pair