BDBM50300132 CHEMBL584972::N-heptanoyl-L-homoserine lactone

SMILES: CCCCCCC(=O)N[C@H]1CCOC1=O

InChI Key: InChIKey=FTMZLSDESAOPSZ-VIFPVBQESA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50300132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein luxR (Vibrio fischeri)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein traR (Rhizobium radiobacter)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSL				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein lasR (Pseudomonas aeruginosa)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282
					More data for this Ligand-Target Pair
Transcriptional activator protein lasR (Pseudomonas aeruginosa)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena-Facultad de Ciencias Exactas y Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa LasR				Eur J Med Chem 45: 608-15 (2010) Article DOI: 10.1016/j.ejmech.2009.11.004 BindingDB Entry DOI: 10.7270/Q2ZC83SP
					More data for this Ligand-Target Pair
Transcriptional activator protein luxR (Vibrio fischeri)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Antagonist activity at Aliivibrio fischeri ES114 LuxR after 4 to 8 hrs by luminescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282
					More data for this Ligand-Target Pair
Transcriptional activator protein traR (Rhizobium radiobacter)	BDBM50300132 (CHEMBL584972 | N-heptanoyl-L-homoserine lactone) Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena-Facultad de Ciencias Exactas y Curated by ChEMBL					Assay Description Inhibition of Agrobacterium tumefaciens TraR				Eur J Med Chem 45: 608-15 (2010) Article DOI: 10.1016/j.ejmech.2009.11.004 BindingDB Entry DOI: 10.7270/Q2ZC83SP
					More data for this Ligand-Target Pair