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SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCCC(C2)C(N)=O)ncc1Br

InChI Key: InChIKey=GJBCCJLNWRJQSU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300390   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM50300390
PNG
(1-(4-(5-bromo-4-(2-(N-methylsulfamoyl)phenylamino)...)
Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCCC(C2)C(N)=O)ncc1Br
Show InChI InChI=1S/C24H28BrN7O4S/c1-27-37(34,35)21-8-4-3-7-19(21)29-23-17(25)13-28-24(31-23)30-18-10-9-16(12-20(18)36-2)32-11-5-6-15(14-32)22(26)33/h3-4,7-10,12-13,15,27H,5-6,11,14H2,1-2H3,(H2,26,33)(H2,28,29,30,31)
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n/an/a 200n/an/an/an/an/an/a



GVK Biosciences Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human GST-fused ZAP-70 expressed in Sf9 cells

Eur J Med Chem 44: 4793-800 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.018
BindingDB Entry DOI: 10.7270/Q25X290Z
More data for this
Ligand-Target Pair