BDBM50300396 2-(2-(1H-indazol-7-ylamino)-5-bromopyrimidin-4-ylamino)-N-methylbenzenesulfonamide::CHEMBL584170

SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cccc3cn[nH]c23)ncc1Br

InChI Key: InChIKey=AOBVNSLSAOQIPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM50300396 (2-(2-(1H-indazol-7-ylamino)-5-bromopyrimidin-4-yla...) Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cccc3cn[nH]c23)ncc1Br Show InChI InChI=1S/C18H16BrN7O2S/c1-20-29(27,28)15-8-3-2-6-13(15)23-17-12(19)10-21-18(25-17)24-14-7-4-5-11-9-22-26-16(11)14/h2-10,20H,1H3,(H,22,26)(H2,21,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
GVK Biosciences Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human GST-fused ZAP-70 expressed in Sf9 cells				Eur J Med Chem 44: 4793-800 (2009) Article DOI: 10.1016/j.ejmech.2009.07.018 BindingDB Entry DOI: 10.7270/Q25X290Z
					More data for this Ligand-Target Pair