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SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(F)cc2F)ncc1Br

InChI Key: InChIKey=YXMUIXGURFNGQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300403   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM50300403
PNG
(2-(5-bromo-2-(2,4-difluorophenylamino)pyrimidin-4-...)
Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(F)cc2F)ncc1Br
Show InChI InChI=1S/C17H14BrF2N5O2S/c1-21-28(26,27)15-5-3-2-4-14(15)23-16-11(18)9-22-17(25-16)24-13-7-6-10(19)8-12(13)20/h2-9,21H,1H3,(H2,22,23,24,25)
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PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



GVK Biosciences Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human GST-fused ZAP-70 expressed in Sf9 cells

Eur J Med Chem 44: 4793-800 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.018
BindingDB Entry DOI: 10.7270/Q25X290Z
More data for this
Ligand-Target Pair