BDBM50300405 2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-4,5-difluoro-N-methylbenzamide::CHEMBL574385

SMILES: CNC(=O)c1cc(F)c(F)cc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl

InChI Key: InChIKey=UQETZOYIXIGUPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM50300405 (2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...) Show SMILES CNC(=O)c1cc(F)c(F)cc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl Show InChI InChI=1S/C23H23ClF2N6O3/c1-27-22(33)14-10-16(25)17(26)11-19(14)29-21-15(24)12-28-23(31-21)30-18-4-3-13(9-20(18)34-2)32-5-7-35-8-6-32/h3-4,9-12H,5-8H2,1-2H3,(H,27,33)(H2,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GVK Biosciences Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human GST-fused ZAP-70 expressed in Sf9 cells				Eur J Med Chem 44: 4793-800 (2009) Article DOI: 10.1016/j.ejmech.2009.07.018 BindingDB Entry DOI: 10.7270/Q25X290Z
					More data for this Ligand-Target Pair