BDBM50300530 (1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-tolylpropan-2-ol::CHEMBL577825

SMILES: CNC[C@@H](O)[C@H](c1cccc(C)c1)n1ccc2ccccc12

InChI Key: InChIKey=UUZFTXGGHPBIFW-MOPGFXCFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50300530 ((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-toly...) Show SMILES CNC[C@@H](O)[C@H](c1cccc(C)c1)n1ccc2ccccc12 |r| Show InChI InChI=1S/C19H22N2O/c1-14-6-5-8-16(12-14)19(18(22)13-20-2)21-11-10-15-7-3-4-9-17(15)21/h3-12,18-20,22H,13H2,1-2H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 5807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.07.050 BindingDB Entry DOI: 10.7270/Q2H70FV8
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50300530 ((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-toly...) Show SMILES CNC[C@@H](O)[C@H](c1cccc(C)c1)n1ccc2ccccc12 |r| Show InChI InChI=1S/C19H22N2O/c1-14-6-5-8-16(12-14)19(18(22)13-20-2)21-11-10-15-7-3-4-9-17(15)21/h3-12,18-20,22H,13H2,1-2H3/t18-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human SERT expressed in JAR cells				Bioorg Med Chem Lett 19: 5807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.07.050 BindingDB Entry DOI: 10.7270/Q2H70FV8
					More data for this Ligand-Target Pair