BDBM50300679 5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL584382

SMILES: CCc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1

InChI Key: InChIKey=VENUWBMCARDXRR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300679 (5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C13H12N4O/c1-2-11-14-10-8-17(9-6-4-3-5-7-9)16-12(10)13(18)15-11/h3-8H,2H2,1H3,(H,14,15,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300679 (5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C13H12N4O/c1-2-11-14-10-8-17(9-6-4-3-5-7-9)16-12(10)13(18)15-11/h3-8H,2H2,1H3,(H,14,15,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair