Found 6 hits for monomerid = 50301110 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of ADAM-10 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of HER-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-3 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-9 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50301110
((5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihyd...)Show SMILES ONC(=O)[C@H]1C[C@@H](CN[C@@H]1C(=O)N1CC=C(C1)c1ccccc1)OC(=O)N1CCCC1 |r,c:15| Show InChI InChI=1S/C22H28N4O5/c27-20(24-30)18-12-17(31-22(29)25-9-4-5-10-25)13-23-19(18)21(28)26-11-8-16(14-26)15-6-2-1-3-7-15/h1-3,6-8,17-19,23,30H,4-5,9-14H2,(H,24,27)/t17-,18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-1 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |