BDBM50301383 (E/Z)-5-bromo-3-(4-methoxyphenylimino)indolin-2-one::CHEMBL572223

SMILES: COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(Br)cc12

InChI Key: InChIKey=WGAFLWYXQOACCE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM50301383 ((E/Z)-5-bromo-3-(4-methoxyphenylimino)indolin-2-on...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(Br)cc12 Show InChI InChI=1S/C15H11BrN2O2/c1-20-11-5-3-10(4-6-11)17-14-12-8-9(16)2-7-13(12)18-15(14)19/h2-8H,1H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair