BDBM50301805 1-(4-(5-methyl-1-(pyridin-3-yl)-1H-1,2,3-triazol-4-yl)phenyl)ethanone::CHEMBL565972

SMILES: CC(=O)c1ccc(cc1)-c1nnn(c1C)-c1cccnc1

InChI Key: InChIKey=PNXOPQMGMKWEHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50301805 (1-(4-(5-methyl-1-(pyridin-3-yl)-1H-1,2,3-triazol-4...) Show SMILES CC(=O)c1ccc(cc1)-c1nnn(c1C)-c1cccnc1 Show InChI InChI=1S/C16H14N4O/c1-11-16(14-7-5-13(6-8-14)12(2)21)18-19-20(11)15-4-3-9-17-10-15/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...				Bioorg Med Chem Lett 19: 5310-3 (2009) Article DOI: 10.1016/j.bmcl.2009.07.145 BindingDB Entry DOI: 10.7270/Q26H4HGN
					More data for this Ligand-Target Pair