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SMILES: Clc1ccc(NC(=O)c2ccccn2)cc1-c1ccccn1

InChI Key: InChIKey=BGFXPVGQOOIBFD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sonic hedgehog protein


(Mus musculus (Mouse))		BDBM50302130
PNG
(CHEMBL576466 | N-(4-chloro-3-(pyridin-2-yl)phenyl)...)
Show SMILES Clc1ccc(NC(=O)c2ccccn2)cc1-c1ccccn1
Show InChI InChI=1S/C17H12ClN3O/c18-14-8-7-12(11-13(14)15-5-1-3-9-19-15)21-17(22)16-6-2-4-10-20-16/h1-11H,(H,21,22)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assay

Bioorg Med Chem Lett 19: 5576-81 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.049
BindingDB Entry DOI: 10.7270/Q21R6QMJ
More data for this
Ligand-Target Pair