BDBM50302133 CHEMBL572230::N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide

SMILES: Clc1ccc(NC(=O)c2ccccc2)cc1-c1ccccn1

InChI Key: InChIKey=KDCMHGOCDYEERH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50302133 (CHEMBL572230 | N-(4-chloro-3-(pyridin-2-yl)phenyl)...) Show SMILES Clc1ccc(NC(=O)c2ccccc2)cc1-c1ccccn1 Show InChI InChI=1S/C18H13ClN2O/c19-16-10-9-14(12-15(16)17-8-4-5-11-20-17)21-18(22)13-6-2-1-3-7-13/h1-12H,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assay				Bioorg Med Chem Lett 19: 5576-81 (2009) Article DOI: 10.1016/j.bmcl.2009.08.049 BindingDB Entry DOI: 10.7270/Q21R6QMJ
					More data for this Ligand-Target Pair