BDBM50302344 CHEMBL565627::N-(1-(4'-(4-(2-methoxyethyl)phenoxy)biphenyl-4-yl)ethyl)acetamide

SMILES: COCCc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1

InChI Key: InChIKey=NWGBBWJTHKXIFA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM50302344 (CHEMBL565627 | N-(1-(4'-(4-(2-methoxyethyl)phenoxy...) Show SMILES COCCc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-18(26-19(2)27)21-6-8-22(9-7-21)23-10-14-25(15-11-23)29-24-12-4-20(5-13-24)16-17-28-3/h4-15,18H,16-17H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase (Homo sapiens (Human))	BDBM50302344 (CHEMBL565627 | N-(1-(4'-(4-(2-methoxyethyl)phenoxy...) Show SMILES COCCc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-18(26-19(2)27)21-6-8-22(9-7-21)23-10-14-25(15-11-23)29-24-12-4-20(5-13-24)16-17-28-3/h4-15,18H,16-17H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM50302344 (CHEMBL565627 | N-(1-(4'-(4-(2-methoxyethyl)phenoxy...) Show SMILES COCCc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-18(26-19(2)27)21-6-8-22(9-7-21)23-10-14-25(15-11-23)29-24-12-4-20(5-13-24)16-17-28-3/h4-15,18H,16-17H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM50302344 (CHEMBL565627 | N-(1-(4'-(4-(2-methoxyethyl)phenoxy...) Show SMILES COCCc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-18(26-19(2)27)21-6-8-22(9-7-21)23-10-14-25(15-11-23)29-24-12-4-20(5-13-24)16-17-28-3/h4-15,18H,16-17H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair