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SMILES: N[C@@H](CCN1CCC[C@H]1c1ncn(n1)-c1ccccc1)Cc1ccccc1F

InChI Key: InChIKey=HJPQBIGKUTUIJQ-RXVVDRJESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302950   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50302950
PNG
((R)-1-(2-fluorophenyl)-4-((S)-2-(1-phenyl-1H-1,2,4...)
Show SMILES N[C@@H](CCN1CCC[C@H]1c1ncn(n1)-c1ccccc1)Cc1ccccc1F |r|
Show InChI InChI=1S/C22H26FN5/c23-20-10-5-4-7-17(20)15-18(24)12-14-27-13-6-11-21(27)22-25-16-28(26-22)19-8-2-1-3-9-19/h1-5,7-10,16,18,21H,6,11-15,24H2/t18-,21-/m0/s1
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MMDB

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n/an/a 62n/an/an/an/an/an/a



Santhera Pharmaceuticals (Switzerland) Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay

Bioorg Med Chem Lett 19: 6340-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.078
BindingDB Entry DOI: 10.7270/Q2WS8TB2
More data for this
Ligand-Target Pair