BDBM50302962 (R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL567279
SMILES: CC(=O)N1CC(C1)c1noc(n1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F
InChI Key: InChIKey=KNOTZXIQSRQETG-KDOFPFPSSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50302962![]() ((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of DPP7 | Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM50302962![]() ((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human DPP9 expressed in baculovirus system after 30 mins by continuous fluorescent assay | Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50302962![]() ((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay | Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase VIII (Homo sapiens (Human)) | BDBM50302962![]() ((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human DPP8 expressed in baculovirus system after 15 mins by continuous fluorescent assay | Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Homo sapiens (Human)) | BDBM50302962![]() ((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL | Assay Description Inhibition of human POP expressed in Escherichia coli after 30 mins by continuous fluorescent assay | Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 | |||||||||||
More data for this Ligand-Target Pair |