BDBM50303867 4-Amino-5-fluoro-7-bromo-1-isobutyl-2-[5-(2-phosphono)furanyl]-benzimidazole::CHEMBL577117

SMILES: CC(C)Cn1c(nc2c(N)c(F)cc(Br)c12)-c1ccc(o1)P(O)(O)=O

InChI Key: InChIKey=YXKXJQUMLFQSLP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase (Rattus norvegicus)	BDBM50303867 (4-Amino-5-fluoro-7-bromo-1-isobutyl-2-[5-(2-phosph...) Show SMILES CC(C)Cn1c(nc2c(N)c(F)cc(Br)c12)-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C15H16BrFN3O4P/c1-7(2)6-20-14-8(16)5-9(17)12(18)13(14)19-15(20)10-3-4-11(24-10)25(21,22)23/h3-5,7H,6,18H2,1-2H3,(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of rat liver FBPase 1				J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50303867 (4-Amino-5-fluoro-7-bromo-1-isobutyl-2-[5-(2-phosph...) Show SMILES CC(C)Cn1c(nc2c(N)c(F)cc(Br)c12)-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C15H16BrFN3O4P/c1-7(2)6-20-14-8(16)5-9(17)12(18)13(14)19-15(20)10-3-4-11(24-10)25(21,22)23/h3-5,7H,6,18H2,1-2H3,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human liver FBPase 1				J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ
					More data for this Ligand-Target Pair