BDBM50303887 4-Amino-1-cyclopentylmethyl-2-[2-(5-phosphono)furanyl]benzimidazole::CHEMBL571879

SMILES: Nc1cccc2n(CC3CCCC3)c(nc12)-c1ccc(o1)P(O)(O)=O

InChI Key: InChIKey=OPEAKWUBZWEFEN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase (Rattus norvegicus)	BDBM50303887 (4-Amino-1-cyclopentylmethyl-2-[2-(5-phosphono)fura...) Show SMILES Nc1cccc2n(CC3CCCC3)c(nc12)-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C17H20N3O4P/c18-12-6-3-7-13-16(12)19-17(20(13)10-11-4-1-2-5-11)14-8-9-15(24-14)25(21,22)23/h3,6-9,11H,1-2,4-5,10,18H2,(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of rat liver FBPase 1				J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50303887 (4-Amino-1-cyclopentylmethyl-2-[2-(5-phosphono)fura...) Show SMILES Nc1cccc2n(CC3CCCC3)c(nc12)-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C17H20N3O4P/c18-12-6-3-7-13-16(12)19-17(20(13)10-11-4-1-2-5-11)14-8-9-15(24-14)25(21,22)23/h3,6-9,11H,1-2,4-5,10,18H2,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human liver FBPase 1				J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ
					More data for this Ligand-Target Pair