BDBM50304511 6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine::CHEMBL594730

SMILES: CCc1cc2c(ncnc2s1)N1CCN(C)CC1

InChI Key: InChIKey=ZAYUCMVNISSUTM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304511 (6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyr...) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(C)CC1 Show InChI InChI=1S/C13H18N4S/c1-3-10-8-11-12(14-9-15-13(11)18-10)17-6-4-16(2)5-7-17/h8-9H,3-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50304511 (6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyr...) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(C)CC1 Show InChI InChI=1S/C13H18N4S/c1-3-10-8-11-12(14-9-15-13(11)18-10)17-6-4-16(2)5-7-17/h8-9H,3-7H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair