null

SMILES: CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C#N)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=VULXLZZXKAOWKQ-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50304970 ((S)-2-chloro-4-((2-cyanobenzyl)(1-(methylsulfonyl)...) Show SMILES CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C#N)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN4O2S/c1-28(26,27)24-9-8-19(14-24)25(13-17-5-3-2-4-15(17)11-22)18-7-6-16(12-23)20(21)10-18/h2-7,10,19H,8-9,13-14H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR in human T47D cells				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50304970 ((S)-2-chloro-4-((2-cyanobenzyl)(1-(methylsulfonyl)...) Show SMILES CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C#N)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN4O2S/c1-28(26,27)24-9-8-19(14-24)25(13-17-5-3-2-4-15(17)11-22)18-7-6-16(12-23)20(21)10-18/h2-7,10,19H,8-9,13-14H2,1H3/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50304970 ((S)-2-chloro-4-((2-cyanobenzyl)(1-(methylsulfonyl)...) Show SMILES CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C#N)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN4O2S/c1-28(26,27)24-9-8-19(14-24)25(13-17-5-3-2-4-15(17)11-22)18-7-6-16(12-23)20(21)10-18/h2-7,10,19H,8-9,13-14H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50304970 ((S)-2-chloro-4-((2-cyanobenzyl)(1-(methylsulfonyl)...) Show SMILES CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C#N)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN4O2S/c1-28(26,27)24-9-8-19(14-24)25(13-17-5-3-2-4-15(17)11-22)18-7-6-16(12-23)20(21)10-18/h2-7,10,19H,8-9,13-14H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PR				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair