null

SMILES: CC(C)OC(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=GQWYUVJFOCQPDO-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50304982 ((S)-isopropyl 3-((3-chloro-4-cyanophenyl)(5-fluoro...) Show SMILES CC(C)OC(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H25ClFN3O2/c1-15(2)30-23(29)27-9-8-21(14-27)28(13-18-10-19(25)6-4-16(18)3)20-7-5-17(12-26)22(24)11-20/h4-7,10-11,15,21H,8-9,13-14H2,1-3H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	233	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR in human T47D cells				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50304982 ((S)-isopropyl 3-((3-chloro-4-cyanophenyl)(5-fluoro...) Show SMILES CC(C)OC(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H25ClFN3O2/c1-15(2)30-23(29)27-9-8-21(14-27)28(13-18-10-19(25)6-4-16(18)3)20-7-5-17(12-26)22(24)11-20/h4-7,10-11,15,21H,8-9,13-14H2,1-3H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50304982 ((S)-isopropyl 3-((3-chloro-4-cyanophenyl)(5-fluoro...) Show SMILES CC(C)OC(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H25ClFN3O2/c1-15(2)30-23(29)27-9-8-21(14-27)28(13-18-10-19(25)6-4-16(18)3)20-7-5-17(12-26)22(24)11-20/h4-7,10-11,15,21H,8-9,13-14H2,1-3H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50304982 ((S)-isopropyl 3-((3-chloro-4-cyanophenyl)(5-fluoro...) Show SMILES CC(C)OC(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H25ClFN3O2/c1-15(2)30-23(29)27-9-8-21(14-27)28(13-18-10-19(25)6-4-16(18)3)20-7-5-17(12-26)22(24)11-20/h4-7,10-11,15,21H,8-9,13-14H2,1-3H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PR				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair