BDBM50304989 (S)-2-chloro-4-((1-(methylsulfonyl)pyrrolidin-3-yl)(3-(trifluoromethyl)benzyl)amino)benzonitrile::CHEMBL589854

SMILES: CS(=O)(=O)N1CC[C@@H](C1)N(Cc1cccc(c1)C(F)(F)F)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=LOEUVGBTLRPLCH-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50304989 ((S)-2-chloro-4-((1-(methylsulfonyl)pyrrolidin-3-yl...) Show SMILES CS(=O)(=O)N1CC[C@@H](C1)N(Cc1cccc(c1)C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3O2S/c1-30(28,29)26-8-7-18(13-26)27(17-6-5-15(11-25)19(21)10-17)12-14-3-2-4-16(9-14)20(22,23)24/h2-6,9-10,18H,7-8,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PR				Bioorg Med Chem Lett 20: 371-4 (2010) Article DOI: 10.1016/j.bmcl.2009.10.092 BindingDB Entry DOI: 10.7270/Q2057G17
					More data for this Ligand-Target Pair