BDBM50305115 5-(4'-cyanobiphenyl-4-yloxy)-N-hydroxypentanamide::CHEMBL591321

SMILES: ONC(=O)CCCCOc1ccc(cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=AJPODVJJWNQXJU-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50305115 (5-(4'-cyanobiphenyl-4-yloxy)-N-hydroxypentanamide ...) Show SMILES ONC(=O)CCCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C18H18N2O3/c19-13-14-4-6-15(7-5-14)16-8-10-17(11-9-16)23-12-2-1-3-18(21)20-22/h4-11,22H,1-3,12H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50305115 (5-(4'-cyanobiphenyl-4-yloxy)-N-hydroxypentanamide ...) Show SMILES ONC(=O)CCCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C18H18N2O3/c19-13-14-4-6-15(7-5-14)16-8-10-17(11-9-16)23-12-2-1-3-18(21)20-22/h4-11,22H,1-3,12H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
					More data for this Ligand-Target Pair