BindingDB logo
myBDB logout

null

SMILES: C(OCc1ccccc1)C1Nc2ccccc2-c2ccnc3[nH]cc1c23

InChI Key: InChIKey=WPMDUWWKHBVKST-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305165   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM50305165
PNG
(9-[(benzyloxy)methyl]-8,12,14-triazatetracyclo[8.6...)
Show SMILES C(OCc1ccccc1)C1Nc2ccccc2-c2ccnc3[nH]cc1c23
Show InChI InChI=1S/C22H19N3O/c1-2-6-15(7-3-1)13-26-14-20-18-12-24-22-21(18)17(10-11-23-22)16-8-4-5-9-19(16)25-20/h1-12,20,25H,13-14H2,(H,23,24)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.80E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of JAK2 by radiometric assay

Bioorg Med Chem Lett 20: 153-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.021
BindingDB Entry DOI: 10.7270/Q2PN95RQ
More data for this
Ligand-Target Pair