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SMILES: N1C(c2c[nH]c3nccc(-c4ccccc14)c23)c1ccccc1

InChI Key: InChIKey=ZQVHTTDMWSMUTQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305169   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM50305169
PNG
(9-phenyl-8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^...)
Show SMILES N1C(c2c[nH]c3nccc(-c4ccccc14)c23)c1ccccc1
Show InChI InChI=1S/C20H15N3/c1-2-6-13(7-3-1)19-16-12-22-20-18(16)15(10-11-21-20)14-8-4-5-9-17(14)23-19/h1-12,19,23H,(H,21,22)
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 370n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of JAK2 by radiometric assay

Bioorg Med Chem Lett 20: 153-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.021
BindingDB Entry DOI: 10.7270/Q2PN95RQ
More data for this
Ligand-Target Pair