BDBM50305695 4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-4-methylpentane-1,2-diol hydrochloride::CHEMBL604581

SMILES: CC(C)(CC(O)CO)c1nnc2ccc(Sc3ccc(F)cc3F)cn12

InChI Key: InChIKey=YYDMYLLCCVAJRV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50305695 (4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...) Show SMILES CC(C)(CC(O)CO)c1nnc2ccc(Sc3ccc(F)cc3F)cn12 Show InChI InChI=1S/C18H19F2N3O2S/c1-18(2,8-12(25)10-24)17-22-21-16-6-4-13(9-23(16)17)26-15-5-3-11(19)7-14(15)20/h3-7,9,12,24-25H,8,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38 alpha				Bioorg Med Chem Lett 20: 469-73 (2010) Article DOI: 10.1016/j.bmcl.2009.11.114 BindingDB Entry DOI: 10.7270/Q2G160XP
					More data for this Ligand-Target Pair