BDBM50305705 3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-4-methylbenzoic acid hydrochloride::CHEMBL592990

SMILES: Cc1ccc(cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(O)=O

InChI Key: InChIKey=LCBYFZAUVTYEDH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50305705 (3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...) Show SMILES Cc1ccc(cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(O)=O Show InChI InChI=1S/C20H13F2N3O2S/c1-11-2-3-12(20(26)27)8-15(11)19-24-23-18-7-5-14(10-25(18)19)28-17-6-4-13(21)9-16(17)22/h2-10H,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38 alpha				Bioorg Med Chem Lett 20: 469-73 (2010) Article DOI: 10.1016/j.bmcl.2009.11.114 BindingDB Entry DOI: 10.7270/Q2G160XP
					More data for this Ligand-Target Pair