BDBM50306172 5-fluoro-2-(4-(1-methylpiperidine-4-carboxamido)phenyl)-2H-indazole-7-carboxamide::CHEMBL593124

SMILES: CN1CCC(CC1)C(=O)Nc1ccc(cc1)-n1cc2cc(F)cc(C(N)=O)c2n1

InChI Key: InChIKey=UNLDXNGUOQSKBC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50306172 (5-fluoro-2-(4-(1-methylpiperidine-4-carboxamido)ph...) Show SMILES CN1CCC(CC1)C(=O)Nc1ccc(cc1)-n1cc2cc(F)cc(C(N)=O)c2n1 Show InChI InChI=1S/C21H22FN5O2/c1-26-8-6-13(7-9-26)21(29)24-16-2-4-17(5-3-16)27-12-14-10-15(22)11-18(20(23)28)19(14)25-27/h2-5,10-13H,6-9H2,1H3,(H2,23,28)(H,24,29)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assay				Bioorg Med Chem Lett 20: 488-92 (2010) Article DOI: 10.1016/j.bmcl.2009.11.127 BindingDB Entry DOI: 10.7270/Q2W37WFZ
					More data for this Ligand-Target Pair