BDBM50306367 5-(4-(2-chloro-4-(trifluoromethyl)phenoxy)benzyl)thiazolidine-2,4-dione::CHEMBL607983

SMILES: Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(cc2Cl)C(F)(F)F)cc1

InChI Key: InChIKey=WRBDKRNCNYGKHF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306367 (5-(4-(2-chloro-4-(trifluoromethyl)phenoxy)benzyl)t...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(cc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C17H11ClF3NO3S/c18-12-8-10(17(19,20)21)3-6-13(12)25-11-4-1-9(2-5-11)7-14-15(23)22-16(24)26-14/h1-6,8,23H,7H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA				Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS
					More data for this Ligand-Target Pair